Press Releases

Alterity Therapeutics, a biotechnology company dedicated to developing disease modifying treatments for neurodegenerative diseases, today announced positive interim data from the ATH434-202 open-label Phase 2 clinical trial in patients with multiple system atrophy (MSA). ATH434 has been shown preclinically to reduce α-synuclein pathology and preserve neuronal function by restoring normal iron balance in the brain. The interim analysis included clinical and biomarker data on 7

Lisata Therapeutics, Inc., a clinical-stage pharmaceutical company developing innovative therapies for the treatment of advanced solid tumors and other serious diseases, announced today the early completion of enrollment in its Phase 2a BOLSTER trial evaluating certepetide (formerly LSTA1), Lisata’s investigational product, as a treatment for first-line cholangiocarcinoma (“CCA”). This key milestone comes nearly six months sooner than originally expected. The BOLST

Passage Bio, Inc., a clinical-stage genetic medicines company focused on improving the lives of patients with neurodegenerative diseases, today announced that the company received positive feedback in its Type C meeting process with the U.S. Food and Drug Administration (FDA) on its proposal to evaluate PBFT02 for treating frontotemporal dementia (FTD) patients with mutations in the C9orf72 gene. Compelling preclinical evidence, coupled with available safety and robust progranulin (PGRN) expr

Dermaliq Therapeutics, Inc. (Dermaliq), a private, clinical stage dermatology and medical aesthetics company, today announced statistically significant topline data from a randomized, blinded, vehicle and comparator-controlled clinical Phase 1b/2a trial in men with androgenetic alopecia (male pattern baldness, AGA) for its topical product candidate DLQ01, a prostaglandin F2α analog, based on Dermaliq’s novel hyliQ® technology platform. The study objectives were to ev

MediWound Ltd., the world leader in next-generation enzymatic therapeutics for tissue repair, today announced it has entered into a definitive share purchase agreement with several new and existing investors, including Mölnlycke Health Care ("Mölnlycke"), a world-leading MedTech company specializing in solutions for wound care and surgical procedures. The agreement includes the sale and purchase of 1,453,488 shares of the Company’s ordinary shares, each wit

FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the results of its study comparing the coadministration of intranasal M2SR and the high dose flu shot in an unprecedented study of older adults ages 65-85 years. The findings are reported today in the journal Lancet Infectious Diseases (https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00351-7/fulltext). The study evaluated the safety, tolerability,

Verastem Oncology, a biopharmaceutical company committed to advancing new medicines for patients with cancer, today announced that the first patient has been dosed in a Phase 1/2 trial in China, conducted by GenFleet Therapeutics, evaluating GFH375/VS-7375, a KRAS G12D (ON/OFF) inhibitor. GFH375/VS-7375, was selected as Verastem’s lead discovery program from its collaboration with GenFleet established in 2023. GFH375/VS-7375 is an oral, potent and selective KRAS G12D dual inhi

Palisade Bio, Inc., a biopharmaceutical company focused on developing and advancing novel therapeutics for patients living with autoimmune, inflammatory, and fibrotic diseases, today announced the successful completion of the first Good Manufacturing Practice (GMP) batch of its drug substance PALI-2108, an orally administered, locally acting colon-specific phosphodiesterase-4 (PDE4) inhibitor prodrug in development for patients affected by UC. The GMP manufacturing was conducted in

MIMETAS, a global leader in organ-on-chip-based disease models for drug discovery and development, announce an Investigational New Drug (IND) filing by argenx, supported by data from MIMETAS. The preclinical collaboration focused on investigating the effects of a novel candidate in a human in vitro disease assay in MIMETAS’ OrganoPlate platform. Its results contributed to an IND application by argenx, representing an important milestone for both companies. The research seamles

Merz Therapeutics today announced the acquisition of INBRIJA ® and AMPYRA ®, and related assets from Acorda Therapeutics, Inc. AMPYRA ® is approved by the Food and Drug Administration (FDA) in the United States and marketed as FAMPYRA in the European Union and other territories worldwide. The transaction was completed in a court-structured 363 sale under the US Bankruptcy Code. The closing of this deal, valued at $185 million in cash, strengthens Merz Therapeutics’ market po