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Freeze drying cycles are designed with specific product, formulation, batch and equipment parameters in mind. A change in any of these may affect the behavior of the product during the cycle, or may make the cycle inefficient. Production dryers typically have different capabilities to smaller R&D systems in terms of achievable temperatures, condenser load and process energy.
A cycle that is optimized for the lab may not be suitable or even possible on larger systems. For these reasons BTL offers process scale-up and optimisation services, to ensure that your process is right for your product and equipment. Initial analyses with freeze drying instruments Lyostat and Lyotherm provide key data about the essential characteristics of the product which are used to draft an initial cycle.
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