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SYFPAC® is an acronym for “System for Filling Parenterals Aseptically into Containers of plastic materials”, while SVP stands for “Small Volume Parenterals.”
The SYFPAC® SVP blow moulded fill seal machines were specifically designed for containers which have a filled volume between 0.25 ml up to 50 ml, for aseptic primary packaging of: Injectable solutions, ophthalmologic preparations, ear drops, preparations for aerosol therapy, respules, disinfectants, diluents, antibiotics and solutions for reconstitution.
The blow fill seal machine special filling systems can be developed to package pastes, creams, thixotropic substances, suspensions, substances which set very quickly and substances which need protection from light and from atmospheric oxygen.
Temperature of the liquid while filling should be typically between 4°C to 30°C. Modified blow molding machines systems can be developed to handle liquids at higher temperature.
Small volume containers made from plastic blos molding machines using BFS technology present several advantages compared to conventional glass ampoules and vials. Plastic containers are much more convenient and safe to use as they are shatter proof and when opened, do not expose sharp edges. These containers being light weight and virtually unbreakable, can be transported with ease without any loss during transportation. In most cases, either PE or PP is mainly used for making these containers and both the materials are non toxic and compatible with several pharmaceutical substances in accordance with Pharmacopoeia. Both PP and PE are recyclable and environment friendly.
Plastic moulding permits the making of intricate shapes and forms. As a result, the opening and head shape can be customised for different applications. For example:
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