Norliqva
Norliqva
Norliqva is the first FDA-approved liquid solution of amlodipine for the treatment of hypertension for patients 6 and older who are unable or who have trouble swallowing.
Why Norliqva?
- The first FDA-approved liquid solution of amlodipine for hypertension and coronary artery disease
- Approved for adults and children 6 years and older
- Kid-friendly mild peppermint flavor
- Requires no refrigeration or shaking for convenient use
Dysphagia & The Need For Liquid Alternatives
It can include difficulty starting a swallow (oropharyngeal dysphagia), issues in the throat (pharyngeal dysphagia), and the sensation of food being stuck (esophageal dysphagia).
It’s important to optimize treatment plans for patients with dysphagia given these complications. Dysphagic patients who suffer from chronic heart failure, edema caused by heart or liver failure, and/or hypertension are often prescribed medications that are crushed/compounded from tablets into a liquid form.
Unfortunately, liquids derived from crushed/compounded tablets raise concerns about patient safety and efficacy, and they have come under increasing scrutiny from the FDA.
Unfortunately, liquids derived from crushed/compounded tablets raise concerns about patient safety and efficacy, and they have come under increasing scrutiny from the FDA.
CMP’s Portfolio of high value FDA-approved ready-made liquid products are developed for:
- Younger patients who resist or who cannot swallow tablets or capsules
- Older patients who suffer from dysphagia or problems swallowing
- Providers who need safe, compliant, & easy-to-dose alternatives
Patients who may need an oral liquid
- Stroke
- Parkinson’s Disease
- ALS
- Multiple Sclerosis
- Cerebral Palsy
THE RISKS AND CONCERNS OF CRUSHING/COMPOUNDING
Patients who have difficulty swallowing are often given crushed/compounded formulations of the prescriptions. However, crushed/compounded formulations can exhibit a wide variation in potency due to non-uniformity of compounded materials. These dosing inconsistencies of compounded suspensions have long been a persistent challenge for pharmacists and patients.2
Crushed/compounded formulations are not tested for safety or efficacy.
Due to fatalities related to contamination, the FDA recently released stricter guidance regarding crushing/compounding and recommended against using crushed/compounded products considered “essentially copies of a commercially available drug product” without permission, especially if an FDA-approved alternative exists.3
