Cadence System

Cadence™ systems, the industry’s first single-pass tangential flow filtration (TFF) product designed to optimize downstream purification steps in either single-use or re-use modes of operation. Cadence TFF systems harness a new TFF format, the Cadence module, which incorporates a patented fluid path design that enables direct flow operation with a substantial reduction in system hold-up volume. This, along with improved recovery capabilities, increases yield and achieves high product recovery greater than 98 percent.


Cadence single-pass TFF systems do not use a conventional recirculation loop, allowing them to be coupled with other process steps and thereby increase manufacturing throughput. The system design also eliminates or reduces intermediate storage tanks and associated cleaning when using the systems for in-process volume reduction before or after existing steps. Cadence single-pass TFF systems can be easily integrated with other downstream processes such as chromatography or virus removal.


Other Products

Tangential Flow Filtration


Filter Integrity Test Instrument

Rapid Microbiology System

Micro-24 MicroReactor System