Olmetec Plus®
Olmetec Plus®
Olmestran Medoxomil Hydrochlorothiazide
(20mg/12.5 mg), (40mg/12.5 mg), (40mg/25mg)
Tablets for oral use
Product leaflet summary
Therapeutic Indications
OLMETEC PLUS is indicated for the treatment of hypertension. It is also indicated for use in patients whose blood pressure is not adequately controlled by Olmesartan Medoxomil or hydrochlorothiazide alone.
Dosage and Administration
OLMETEC PLUS is administered once daily, with or without food.
Contraindications
Hypersensitivity to the active substances, to any of the excipients or to other sulfonamide-derived substances (since hydrochlorothiazide is a sulfonamide-derived medicinal product).
Olmesartan / Hydrochlorothiazide should not be co-administered with Aliskiren in patients with diabetes mellitus or renal impairment
Severe renal impairment (creatinine clearance
Refractory hypokalaemia, hypercalcaemia, hyponatraemia and symptomatic hyperuricaemia.
Severe hepatic impairment, cholestasis and biliary obstructive disorders.
2nd and 3rd trimester of pregnancy.
In general arteriosclerosis, in patients with ischaemic heart disease or ischaemic cerebrovascular disease, there is always a risk that the excessive blood pressure decrease could result in a myocardial infarction or stroke.
Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of allergy or bronchial asthma, but are more likely in patients with such a history.
Exacerbation or activation of systemic lupus erythematosus has been reported with the use of thiazide diuretics.
This medicinal product contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp-lactase deficiency or glucose-galactose malabsorption should not take this medicinal product.
