High-shear granulators
High-shear granulators
Efficient Mixing and Granulation
PHARMX® high-shear granulators are fully customizable bottom-driven mixing systems engineered to provide homogeneous mixing and efficient granulation. Equipped with an in-bowl, bottom-driven mixing impeller and side-mounted chopper, the PHARMX ensures uniform mixing across a range of R&D, pilot, and production size models.
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MIXER SPECIFICATIONS
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PX1
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PX25
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PX50
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PX100
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PX150
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PX250
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PX400
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PX600
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PX1250
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Total Bowl Vol. (L)
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1, 2, 4, 6, 8, 13
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31
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58
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119
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162
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274
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432
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633
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1286
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Charge- Max. Liters @ Light Bulk, 0.3 - 0.5
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0.9 - 7.5
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28
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58
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107
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150
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246
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389
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569
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1157
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Charge- Min. Liters
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0.3 - 2.5
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8
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15
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30
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42
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69
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109
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159
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324
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Impeller Max. Speed (RPM)
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950
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354
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289
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227
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205
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172
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148
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130
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103
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Impeller Power (HP)
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0.5
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3
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5
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10
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15
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40
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50
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75
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150
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Chopper Speed Range (RPM)
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1500 - 9750
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500 - 4000
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500 - 4000
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500 - 4000
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500 - 4000
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500 - 4000
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500 - 3000
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500 - 3000
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500 - 3000
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Chopper Power (HP)
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0.25
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1
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2
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5
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7.5
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10
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15
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20
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40
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Maximize Your Batch
Uniform Mixing
The dome shaped lid permits product to perform a complete roll over as it moves up the side of the vessel wall. This ensures efficient mixing even when running at larger operating capacities.
Constant Tip Speed
One of the single most important factors in high shear granulation scale up is tip speed of the impeller and chopper tools. Along with tool and bowl geometry, each PHARMX bowl is designed to maintain a constant maximum tip speed across the entire line of models. Each tool has infinitely adjustable tool speed so that scale up from lab to pilot to production is predictable.
Safely Process Hazardous Compounds
For processing potent compounds requiring total containment, we are able to provide customized interchangeable bowls. The bowls can be removed from the console and placed in a glove box/flexible containment structure without any dusting of product from the bowl. Charging and discharging from the mixer bowl is completely contained
Hydraulic Drive System
The hydraulic drive system permits full torque down to ¼ RPM, providing plenty of break-out torque at slow speeds for additional mixing after inspection and continuous discharging to wet milling systems.
