Stevanato Group

Low Delamination Propensity (LDP) Vials

After conducting extensive research on the chemical performance of the glass vial inner surface and the glass forming process parameters, Stevanato Group added SG LDP Vials to its portfolio. These containers are specifically designed to minimize the formation of surface inhomogeneities.

SG LDP Vials are produced with Type 1 Borosilicate glass and have no coating, meaning that there is no need to re-file to Official Authorities.

Watch Video

The issue

The delamination of pharmaceutical glass is a serious issue as it can cause glass particles to appear in a vial. The first step is the formation of an altered layer that leads to the separation of thin glass flakes.

Factors leading to delamination

Drug formulation: aggressive buffers, complexing agents, high pH

Storage Conditions: temperature, time, etc.

Surface Treatments: presence sulfur, coating, etc.

Process and shelf life: depyrogenation, terminal sterilization, etc.

Delamination may cause

Compromised drug integrity

Product recalls

Reduced product shelf life