Charles River

Charles River

251 Ballardvale St, Wilmington, Massachusetts, 01887

Vaccine Development

Vaccine Development

Vaccine development has evolved from conventional prophylactic uses to more complex and novel therapeutic products over time. They are now used to treat diseases such as HIV, West Nile Virus, and SARS, and are currently being developed to help cure COVID-19. These advances require careful scientific consideration of a vaccine’s properties and clinical use. Our experts can work with you on a comprehensive plan to get your vaccine to market.

Vaccine Testing from Discovery to Production

One of the key challenges of effectively developing a vaccine is understanding the immune correlates of protection(1,2). Vaccine development leads to improvements in antigen and adjuvant selection and the design of better vectors – all of which contribute to the success of a vaccine candidate, while keeping appropriate safety testing in mind. It requires appropriate pre-clinical models, testing methodologies, and the availability of necessary immunology tools.

We have decades of experience supporting the vaccine industry with a specific and unique range of products and related services. Our global network of scientific, technical, and regulatory experts provides vaccine developers with the right expertise early in the development process to boost productivity, efficiency, and profitability, and get the safest and most effective vaccines to market.

What’s the Best Approach to Designing a Vaccine?

A vaccine is defined as a biological preparation that stimulates active acquired immunity against a certain disease or pathogen by being an agent that represents the disease-causing microorganism. It’s often made from a weakened or killed form of the microorganism, its toxins, or one of its surface protein antigens. Scientists take many approaches to design vaccines against a pathogenic microorganism. These choices are dictated by the nature of pathogen and the infection, as well as practical considerations about the use of the vaccine. Some of the options include live attenuated, inactivated, DNA, and recombinant subunit vaccines.

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