Cone Mill Calibrator
Cone Mill Calibrator
INTRODUCTION
Particle size reduction, miling or calibrations are some of the denominations given to an important stage in the manufacturing of pharmaceutical solid products, with the purpose of having:
• Reducing and making an uniform size.
• Affecting the solid particles of raw material, dry and wet granulates product.
The particle size, shape and uniformity influence in the solid pharmacy-technical properties:
• How in feeding hoppers.
• Compactability during the compression and with respect to the analytical features of the final produce
• Uniformity of the content.
• Dissolution / Bio-availability.
From the lauching Of High Shear Granulators (MIC) to the pharmaceutical market by means Of which you get firm granulated products, it was necessary to use the Conical Screen Mills (CSM) with the capacity of reducing the particle size of strong granulated material, offering size uniformity, short time process and minimum heat development.
Features
CONCEPTION
The calibration Of the granulated material by means Of the conic screen mill is got when the granule goes into the impact and cutting chamber, and an impeller – which is turning round at high speed — impacts on the material, shatters it and impels it tangentially towards the holes of a selector screen or cone
The conic calibrator CPS Developer has been manufactured with the purpose of offering higher calibration versatility, in such a way that a wide variety of materials could be calibrated with the highest accuracy required.
CPS versatility is due to the possibility 0/5 controllable variable combination, in a unique configuration for each type
Of material to be calibrated:
1. Impeller speed
2. Impeller shape
3. Size and shape of the selector cone boles
4. Distance between the impeller wall and the selector cone wall
5. The total area of holes in the selector cone
Each of these 5 variables will affect on the features of the obtained calibrated material in different ways.
Keeping 4 constants of the 5 variables and changing the fifth one, you could see a change in the features of the obtained calibration in accordance with the following general rules:
• The impeller speed increase or reduction will reduce or increase the medium size of the obtained calibration, respectively.
• The flat side face impeller shall produce finer granules than the round face impeller.
• The cone hole size and shape shall determine the particle medium size and its shape.
• The impeller— cone distance shall affect the medium size.
• The total biggest opening area of the cone shall give the lower proportion of fine granules.
