Isoclean® Healthcare Platform
Isoclean® Healthcare Platform
Esco Pharma’s Isoclean® Healthcare Platform Isolator – Inflatable Seal (HPI-IS) model guarantees the full isolation of a product or process inside an ISO Class 5 or Grade A environment, for high-quality final products.
Along with its inflatable seals and automated dampers, HPI-IS is equipped with an automated pressurehold testing (APHT) and mobile BioVap™ biodecontamination system.
This model can be factory-configured to operate in either a positive or negative pressure mode, with a recirculating or single pass/total exhaust airflow scheme.
Applications:
- Aseptic and/or Potent Compounding
- Pharmacy Compounding
- Sterility Testing
- Cell and Gene Therapy
- Peptide Production
- Biosafety Facility Level 3 or 4
Features
Pressure-tested as per ISO 10648-2:
Selection from three (3) material of constructions:
- Class 2 pressure-leak tight enclosure via auto pressure leak test (factory acceptance test)
- Class 3 via automated pressure test as per ISO 10648-2 (prior to daily tasks)
Superior ISO Class 5 Air Filtration
ULPA filters (as per IEST-RP-CC001.3 and HEPA (H14) filter (as per EN 1822) with a typical efficiency of > 99.999% at 0.1 to 0.3 microns; provide superior ISO Class 5 air cleanliness as per ISO 14644-1.
Automated pressure hold testing (APHT)
APHT provides a smooth way of quantifying the hourly leak rate of the isolator, thus, ensuring the unit’s integrity against leaks while removing the risk for cross-contamination.
Integrated BioVap™ biodecontamination system with H2O2 sensors and catalytic converter.
- Integration of the Biovap™ biodecontamination system allows ease of decontaminating the work chambers with just a press of a button in the Esco HMI.
- HPI-IS with integrated BioVap™ allows master biodecontamination (only performed with internal doors open).
- Master biodecontamination procedure refers to the possibility to biodecontaminate the entire isolator inner chambers (process chamber and pass-through chambers) with a H2O2 mist.
Automated sliding door feature
For closing and opening of the inner pass-through chamber door.
- Facilitates ease of isolation control especially during pressure decay testing and biodecontamination process.
Inflatable seal and automated dampers:
For closing and opening of the inner pass-through chamber door.
- For an improved and safer isolation control during pressure decay testing and bio-decontamination process.
- HPI-IS automated dampers remove the need to manually close/open up the isolator’s dampers every time the unit needs to undergo pressure testing and biodecontamination cycle.
Esco HMI control system
Supervises all cabinet operations and monitors cabinet performance in real-time.
Electromagnetic interlocking doors with time delay effect
Ensures safety and containment during material transfer.
