Vibalogics

Oncolytic Virus

Leading experts in oncolytic virus development and manufacture

The pioneering field of oncolytic viruses and cancer immunotherapies utilize a variety of viruses and vectors under current research and clinical trial – although limited commercial approvals exist to date. These products selectively infect and replicate in tumor tissues driving cell death and immune response. Ongoing trials include products utilizing many viruses as both monotherapy and in combination with additional modalities to drive enhanced efficacy. Our services are here to advance your OV innovation through clinical trial phases and beyond. We provide comprehensive services ranging from process development to GMP drug substance and drug product manufacturing, including aseptic processing capabilities. Our team of experts has a strong track record working with a variety of OV cell lines, including VERO, A549, HEK293 and Primary Chicken Embryonic Fibroblasts (CEFs). We have the capabilities to develop both cell-based (adherent and suspension) and egg-based oncolytic virus products.

Oncolytic Virus Experience

Arenavirus

Adenovirus (Ad)

Herpes Simplex (HSV)

Fowlpox (FPV)

Newcastle Disease (NDV)

Measles (MV)

Vaccinia / Modified Vaccinia Ankara (MVA)

Vesicular Stomatitis (VSV)

Egg-based, Chick Embryo Fibroblasts (CEF), Continuous Cell Lines