AGP Limited

Generic:

Memantine HCl

Therapeutic Class:

All Other Anti Alzheimer Products

Composition:

Afdol oral solution contains memantine HCl in a strength equivalent to 2 mg of memantine HCl in each mL (5 mL =10 mg).
Each Afdol tablet contains 10 mg of memantine hydrochloride.

Description:

Afdol (Memantine hydrochloride) is an orally active N-methyl-D-aspartate (NMDA) receptor antagonist

Indications:

Afdol tablet is indicated for the treatment of moderate to severe dementia of the Alzheimer’s type.

Dosage:

Oral Solution:

The recommended starting dose of AFDOL is 5 mg (2.5 mL) once daily. The recommended target dose is 20 mg/day. The dose should be increased in 5 mg increments to 10 mg/day (2.5 mL twice daily), 15 mg/day (2.5 mL and 5 mL as separate doses), and 20 mg/day (5 mL twice daily). The minimum recommended interval between dose increases is one week.

Tablet:

The recommended starting dose of Afdol is 5 mg once daily. The recommended target dose is 20 mg/day. The dose should be increased in 5 mg increments to 10 mg/day (5 mg twice a day), 15 mg/day (5 mg and 10 mg as separate doses), and 20 mg/day (10 mg twice a day).

Presentations:

• Afdol Tab 10 mg is available in blister pack of 14’s and 56’s.
• Afdol 2 mg/ml Oral Solution is in bottle of 120 ml.