Asymchem Inc

Enzymes

Enzymes

Expanding Expertise In Medically Important Protein Fermentation

Recognizing the growing importance that enzyme therapies represent in pharma company portfolios, Asymchem has made significant investments in cGMP fermentation capabilities and expertise. Like catalytic enzymes, medically important enzymes produced by offer a strong business case:  a highly consistent, high-yield product that can be modified and optimized for manufacture.

Capabilities include:

• Sourcing all required materials under Current Good Manufacturing Practice (cGMP) regulatory conditions.
• 50- and 500-liter nonGMP reactors for bioreactor fermentation of enzyme APIs
• Verification of protein expression
• Fine-tuning’ the technology for production of enzyme APIs
  • Recombinant Expression
  • Enzyme Evolution
  • Immobilization
  • Downstream processing (spray drying, packaging/DP/formulation)
  • Enzyme Activity
• Microbial or mammalian-derived proteins

KNOW. HOW.

In selecting Asymchem for the development of its therapeutic enzyme candidate, AzurRX pointed to Asymchem’s successful track record working with top pharmaceutical companies in the industry and experience in cGMP manufacture of complex recombinant therapies.