BioNavis Ltd

MP-SPR Navi™ 420A ILVES

Get up to speed with 4-channels!

MP-SPR Navi™ 420A ILVES is an ideal solution for molecular interaction studies when high throughput is needed. Minimal dead volume with 4 liquid channels makes the instrument optimal for small molecules and antibody interaction measurements.

Features and benefits

• 4  fluidic  channels for high throughput
• Automation of samples from 96 and 384 well plates  allows  for unattended runs
• Measurements of kinetic constants, concentration and competition analysis, affinity and EC50
• KineticTitration for faster interaction affinity and kinetic measurements
• Exceptionally  wide  angular  range 40˚ – 78˚ enables  measurements  of small  organic  molecules and  large  proteins,  but  also  metallic nanoparticles and live cells. Most importantly, it enables in-line bulk effect separation – PureKinetics™
• Two independent wavelength measurements from each fluidic channel, enabling the detection of thickness and refractive index or conformational changes
• Controlled buffer flow conditions with precise syringe pumps and integrated degasser
• Software switch for serial and individual injections
• Partial loop injections allowing minimized sample consumption
• Complete software package for convenient control of the instrument and easy analysis of the results. 420A ILVES instrument comes with both TraceDrawer™ for  MP-SPR  Navi™ and MP-SPR  Navi™ LayerSolver software. LayerSolver is an advantageous software to determine thickness and RI from multiple wavelength measurements whereas Trace Drawer™ is a powerful  software  for the determination  of affinity and  kinetic constants
• MP-SPR Navi™ instruments utilize optical RI matching elastomer and therefore, sensors are very easy to exchange and remove for  further analysis with other methods such as AFM or microscopy