Botanix Pharmaceuticals

Permetrex™ – Skin Delivery Technology

Permetrex™ – Skin Delivery Technology

Delivering pharmaceuticals to the skin to treat disease is challenging. The skin’s role is to protect the body from a range of chemical and environmental assaults, so bypassing this active system requires an innovative approach. Botanix has exclusively licensed a novel transdermal drug delivery solution known as Permetrex™, which is designed to deliver pharmaceuticals through the skin more effectively. Right to where treatment is needed most.

So what makes Permetrex™ unique?

• It does not utilise chemicals which have a tendency to dry the skin and are therefore undesirable for diseases such as acne, psoriasis and atopic dermatitis;
• It creates substantial chemical potential when applied to the skin, which facilitates the rapid delivery of active pharmaceutical ingredients across the stratum corneum and into the lower layers of the skin;
• It can accommodate other chemicals which can selectively leave parts of the formulation on the skin in a protective coating for extended absorption and/or protection of the skin;
• Transdermal delivery avoids the ‘first-pass’ effect of liver metabolism, potentially enabling lower dosage levels of active pharmaceutical ingredients to be rapidly and reliably absorbed with high bioavailability.