Corel Pharma Chem

KYRON

KYRON® Cross-linked Polymer

Kyron range is derived from cross linked polyacrylic polymer used in pharmaceutical industry for taste masking of bitter drugs and for drug stabilization.

Taste masked complex of bitter drug can be used for following formulations:

• Suspension
• Dry syrup
• Mouth dissolving tablet / Dispersible tablet / Chewable tablet

Advantages

Traditional grades

• Excellent taste masking of bitter drugs.
• Fine powder taste masking.
• Over night soaking is not required for complexation.
• Washing of Kyron / complex is not required.
• Provide self disintegration property to the tablets.
• Improve stability of liquid / solid formulations.
• Allows high drug loading.
• Compatible with most of the drugs.
• Very user-friendly and cost-effective.
• Consistent quality.
• No adverse effect on drug bioavailability.

Ready to use grades (Over traditional grades)

• Excellent taste masking and no bitterness.
• It increases productivity tremendously as it is only single step process.
• No other excipients are required and very easy to formulate.
• Superior quality and good patient compliance.
• Only 15-20 minutes stirring with drug is required for taste masking.
• Drying of complex is not required to formulate dry syrup.

Toxicity

Kyron range is a very high molecular weight polymer so after decomplexation it does not absorb in body and thus it has no toxicological effect.

Storage

At low temperature not exceeding 45°C. Protect from moisture.

Shelf Life

• Traditional grades: Five years from the date of manufacturing in intact condition.
• Ready to use grades: Two years from the date of manufacturing in intact condition.

Packing

• 10 kg and 25 kg fiber drum with polyethylene liner