CARGLUMIC ACID WAYMADE
200 mg Dispersible Tablets, currently approved in selected EU countries
Carglumic acid is a structural analogue of N-acetylglutamate, which is the naturally occurring activator of carbamoyl phosphate synthetase, the first enzyme of the urea cycle. In patients with N-acetylglutamate synthase deficiency, carglumic acid was shown to induce a rapid normalisation of plasma ammonia levels, usually within 24 hours. When the treatment was instituted before any permanent brain damage, patients exhibited normal growth and psychomotor development.
THERAPEUTIC INDICATIONS
Therapeutic indications
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