ROCK MAKER Protein Crystallization Software
ROCK MAKER®Protein Crystallization Software
Manage Your Entire Experiment
One Software from Start to Finish
From designing your experiments to data collection, keep all your data in one spot.
Increase Your Throughput
Machine Learning for Auto-Scoring
Automatically score your drops in minutes with integrated machine learning algorithms.
Design Experiments with Ease
Begin with Only a Few Clicks
Intuitive tools allow users to design screening and optimization experiments in seconds.
One Software for Your Entire Protein Crystallization Workflow
ROCK MAKER® is a Laboratory Information Management System (LIMS) that is there every step of the way, with powerful yet easy-to-use tools that help you get the results you need quickly. ROCK MAKER manages the entire crystallization experimentation process, from designing and dispensing to image viewing and analysis.
To help manage your workflow, ROCK MAKER integrates with:
Design and Manage Experiments with Ease
ROCK MAKER allows you to screen your proteins against sparse screens. The Screen Experiment Wizard makes experiment design a breeze - creating multiple screen experiments for one or more proteins takes less than a minute.
Powerful Experiment Design
Dynamic and Efficient Image Viewing + Scoring
Images taken by ROCK IMAGER are collected by ROCK MAKER, wherein you can compare images and assign scores. Once you’ve found a crystal, you can measure its size and add notes directly to the image itself.
Bring out details of your UV, SONICC, and FRAP images using the leveling histogram or optically zoom in with a Region of Interest (ROI).
View + Score Images with Ease:
Automatically Score Your Drops with MARCO
One bottleneck to protein crystallography is manually scoring those protein drop images, which is often very time-consuming and tedious. With the advent of machine learning has come the ability to have a computer algorithm analyze and score protein drop images. One such technology is the MAchine Recognition of Crystallization Outcomes or MARCO, which can score a 96 well- 1 drop plate in under 3 minutes, with an accuracy of ~94%. MARCO automatically provides a probability of a drop image being either a crystal, precipitate, clear, or other. MARCO is now integrated in ROCK MAKER and can automatically score your drops with just a few clicks.
