Lyophilization Technology, Inc

Development Sciences

Physical inspection evaluates uniformity of appearance in color, texture, shape, structure and provides insight into the relative effects of processing. Using an inspection light box with white and black backgrounds, each sample is viewed at the bottom, sides and top surface of the cake while rotating the container to view all sides. The extent, range and/or consistency for each of the aforementioned attributes are considered and recorded. Color can be characterized as intensity of the color, hue or tint indicating the color tone and shade that reflects lightness to darkness of the color. Product structure can be indicative on more of a microscopic scale described as dense or light, granular or geometric, crystalline looking shapes or composition that make up the arrangement, configuration, pattern, or organization. Texture can range from smooth or fine, appearing like powdered sugar or chalk with indistinguishable finite structure, to a course texture where structure is easily observed. Course texture has a makeup that appears like a collection of open, porous material as in a composition of particles, or assembly of crystalline or granular appearing material.