Recombinant Protein Purification
Advantages of Artificial Protein A Scaffolds
Precision X affinity ligands are small (~6.5 kDa), selective and stable proteins based on our proprietary artificial Protein A scaffold. They no longer have to bind to antibodies’ Fc parts, but instead we engineer new, specific binding characteristics. We also offer adjustable affinities and pH elution profiles, while preventing off-target binding. Our Precision X ligands and matrices possess exceptional binding capacities, high caustic and chemical stability to withstand harsh cleaning-in-place procedures in dozens of sequential downstream processing cycles, for low cost of goods.
Finally, our affinity resins are amenable to generic Protein A leaching assays and can be flexibly used in analytical applications as well.
Precision Capturing® Advantages:
• Selective binding to targets from all biological product classes
• High binding capacity
• High chemical and proteolytic stability
• No internal Cysteines for site-specific matrix-coupling
• Adjustable mild elution conditions
• Amenable to generic Protein A leaching assays
• Ligands also usable for analytical applications
