Polymun has proprietary yeast recombinant porcine trypsinogen that is autocatalytically activated to the active enzyme. This recombinantly manufactured enzyme can replace trypsin derived from animal origin.
Recombinant porcine trypsin has defined activity (e.g. free of chymotrypsin or elastase activity without inhibitor treatment) and is free of animal tissue derived contaminants. Recombinant trypsin is a valuable tool to improve both quality and safety in mammalian cell culture, cell based therapy applications as well as for drug manufacturing processes using trypsin as process enzyme (e.g. insulin production).Polymun has signed a license agreement with Laurus Bio Pvt Ltd (former Richcore Lifesciences Pvt Ltd, Bangalore, India) for the recombinant porcine trypsin technology. Richcore is manufacturing this recombinant porcine trypsin in large scale kilogram quantities for use in GMP processes.
PATENTS
Method for the manufacture of recombinant trypsingranted by: EP 1 250 442; SG 90540; US 7,351,549
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