PPS A/S

IMA LYNFINITY Continuous Aseptic Spray-Freezy-Drying

IMA LYNFINITY Continuous Aseptic Spray-Freezy-Drying

Raising productivity and reducing downtime is now possible in a continuous aseptic process, with constant monitoring from fermentation to final packaging.

LYNFINITY spray-freeze-drying process features a controlled spray of liquid product into a cryogenically cooled freezing chamber. The resultant frozen particles of the liquid product are freeze-dried in the drying module. The drying chamber contents are both transported and heated to promote rapid sublimation and prevent agglomeration.

The continuous spray-freeze-drying process starts with bulk liquid product and ends with the discharge of dried particles, featuring total containment from formulation to powder filling. This enables higher sterility assurance levels, whereas traditional freeze-drying requires additional external material handling, for example during filling. Upon completion of drying, the uniform, dried spherical product allows for the use of a variety of containers (vials, syringes, inhalation systems etc.).

• Designed for continuous process from fermentation to final packaging
• Greater throughput flexibility: minimization of scale up and scale down challenges
• Better quality attributes: improved product uniformity through a gentle drying process