Tornado Spectral Systems

SpectroPort Raman Probe

SpectroPort™ Raman Probe

Full integration with Sartorius Ambr® and STR® platforms

– Seamless integration for quick and simple sampling
– Provides maximum performance and reproducibility
– High-throughput process development

Tornado’s SpectroPort™ Raman Probe is a high-performance sampling device intended for Raman in-line process monitoring of liquid samples in a Sartorius Ambr™ or Biostat STR® system. Its optical design allows for a small size to avoid taking up valuable lab space. Along with Tornado’s HyperFlux™ PRO Plus analyzer, the SpectroPort™ probe measures key process parameters and critical metabolites (i.e. glucose, glutamate, lactate, and others), making it the ideal solution for monitoring bioprocesses and cell cultures.

Raman solution for development and process control

• HyperFlux™ PRO Plus is fully integrated with Sartorius Ambr® 15 and Ambr® 250 high throughput systems
• Direct path to manufacturing with BioPAT® Spectro and Flexsafe® STR single-use bags
• Non-contact sampling, same probe used for both cases
• HyperFlux™ PRO Plus can monitor up to 8 separate STR reactors

Specifications

• Size: 3 x 2.3 x 1.4 inches (8.5 x 5.7 x 3.6 cm) not including fittings or fibers
• Weight: 0.55 lbs. (250 g)
• Excitation Wavelength: 785 nm
• Optical Fiber Connections
  • FC/PC 105 µm NA=0.22 fiber optic cable for excitation
  • FC/PC 300 µm NA=0.22 fiber optic cable for collection
• White Light Fiber Connection
  • SMA 600 µm NA=0.22 fiber optic cable for calibration

Features

• Fully automated data acquisition by Ambr® control computer for creating and deploying SIMCA® calibration models quickly and consistently
• High-throughput process development enhanced by Tornado’s superior measurement speed and precision
• Superior process monitoring and control enable Quality by Design (QbD) approach
• Compact monolithic Raman probe with fully integrated optics, eliminating the risk of misalignment or internal contamination
• Optimized for compatibility with Tornado’s HyperFlux™ PRO Plus Raman analyzer with High Throughput Virtual Slit technology for 10x to 30x higher Raman signal than conventional Raman systems
• High-purity optical elements and short path lengths ensure low background