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Patheon to invest $45 million in spray drying & manufacturing solutions

Patheon to invest $45 million in spray drying & manufacturing solutions


Patheon N.V., a leading global provider of high-quality drug development and delivery solutions to the pharmaceutical sector plans to invest $45 million at key sites across its global network to meet growing customer demand for expanded service capabilities.


As outsourcing of Pharma development and manufacturing services continues to grow, our customers will need even more advanced technologies and customized solutions to meet their business needs, said Michel Lagarde, president of Patheon.

Patheon is investing in the following key areas:

Commercial & Development Spray Drying
The company’s recently acquired site located in Florence, South Carolina, will be adding commercial spray drying capabilities, complementing the existing development capabilities available at the company’s low-solubility center of excellence in Bend, Oregon. The 15,000-sq.-ft. dedicated suite will contain two spray dryers delivering development and commercial scale spray-dried dispersion (SDD) services. The suite is expected to be online in 2019. Spray Drying is a process that creates amorphous solid dispersions and is a key technology utilized to enhance the solubility of poorly soluble drugs.

At the Bend, Oregon site the company plans to expand existing development SDD capabilities with a new cGMP analytical lab, manufacturing suite and additional development scale spray drying. Together, the expertise and capabilities at the Florence and Bend locations provide clients with an end-to-end solution for products with solubility challenges, from development to commercialization, to successfully bring products to market.

Flexible Manufacturing Solutions
Patheon has invested in a new commercial sterile product manufacturing facility in its Monza, Italy site. The facility will house three, 40 sq M lyophilizers with associated eight-headed integrated filling equipment for both lyo and liquid formulations for small and large molecules in a range of vial specifications. The equipment will have full CIP/SIP systems, auto loading for the lyophilizers contained in full RABs systems to ensure the highest level of sterility assurance.

Patheon also plans to expand its sterile product Pharmaceutical Development Services (PDS) at the Monza facility. The sterile suite will contain two 7m2 lyophilizers and associated sterile vial filling line and analytical laboratory. This new facility will serve the company’s clients seeking to develop both small and large molecule injectable products (liquid and lyo formulations) and will be operational in mid-2019.

Patheon will also expand its packaging and serialization capabilities at its Greenville, NC site. The company has built a new filling and packaging suite and upgraded another of its packaging lines with new technology to improve efficiency and reduce change-over time. The newly constructed 4,800-square-foot suite will come online this fall and features a filling and packaging line equipped with an Optel serialization system. The state-of-the-art system includes cameras, pharma proof stations, line master, and bottle and bundle tracker equipment.


Company Name Patheon
Type Expanding Capabilities
Estimated Cost $45 Million



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