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ACK Lysing Buffer is used for lysing red blood cells in samples containing white blood cells.
RBCs are permeable to ammonium chloride, which causes cellular swelling and eventual rupture of the cell membrane.
ACK = Ammonium-Chloride-Potassium
Applications
ACK Lysing Buffer is used to lyse red blood cells in samples, such as EDTA-treated whole blood, buffy coats, and bone marrow.
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