Coriolis Pharma

Aggregate analytics

Orthogonal aggregate analysis with the latest technologies

Qualitative and quantitative data on aggregation is a key asset for assuring quality of biologics. Most protein therapeutics and many other biopharmaceutical molecules are inherently unstable and can undergo aggregation through various pathways. Aggregates of various kinds can be formed, from reversible and non-reversible to soluble and non-soluble. Aggregation can directly influence the efficacy of the therapy be reducing the number of functional molecules, but also indirectly influence efficacy as well as safety of a therapy by inducing side-effects, such as unwanted immunogenicity.

Coriolis – your service partner with scientific excellence – provides a large portfolio of cutting-edge instruments, enabling the orthogonal analysis of the various kinds of aggregates.

Explore our techniques for aggregate analysis and get in touch with our experts to find out how a comprehensive aggregate analysis can be achieved for your sample.