Coriolis Pharma

Particle characterization

Particle characterization from nanometer to the visible size range.

Coriolis is a leading contract laboratory providing analytical services for particle characterization. Particles are potentially present in all biopharmaceutical samples and can originate from various sources. Particles can:

directly derive from the API (active pharmaceutical ingredient e.g., an insufficiently stable protein therapeutic)

be introduced by formulation excipients (e.g., as degradation products or particulate impurities)

be generated by the production process (e.g., pump or filter shed).

Particles occur in various sizes, ranging from a few nanometers up to millimeters, thus spanning over 5 log scales. This is the same size difference as between a footprint and the comet Hale-Bopp.